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1.
Detection of COVID-19 by Quantitative Analysis of Carbonyl Compounds in Exhaled Breath (preprint)
Zhenzhen Xie; James D. Morris; Jianmin Pan; Elizabeth A. Cooke; Saurin R. Sutaria; Dawn Balcom; Subathra Marimuthu; Leslie W. Parrish; Holly Aliesky; Justin J. Huang; Shesh N. Rai; Forest W. Arnold; Jiapeng Huang; Michael H. Nantz; Xiao-An Fu.
ssrn; 2023.
Preprint in English | PREPRINT-SSRN | ID: ppzbmed-10.2139.ssrn.4512976

Subject(s)
COVID-19 , Dyspnea , Ketosis , Communicable Diseases
2.
Persistent SARS-CoV-2 Infection in a Multiple Sclerosis Patient on Ocrelizumab: A Case Report (preprint)
Raghava S. Ambadapoodi; Forest W. Arnold; Julia H. Chariker; Alex Glynn; William Lauer; Subathra Marimuthu; Eric C. Rouchka; Melissa L. Smith; Leslie A. Wolf.
researchsquare; 2023.
Preprint in English | PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-2768759.v1

ABSTRACT

A 44-year-old female patient with multiple sclerosis (MS) treated with ocrelizumab was hospitalized with SARS-CoV-2 pneumonia three times over the course of five months, eventually expiring. Viral sequencing of samples from her first and last admissions suggests a single persistent SARS-CoV-2 infection. We hypothesize that her immunocompromised state, due to MS treatment with an immunosuppressive monoclonal antibody, prevented her from achieving viral clearance.


Subject(s)
COVID-19 , Severe Acute Respiratory Syndrome , Multiple Sclerosis
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